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In-vitro In-vivo Correlation Models for Glibenclamide after Administration of Metformin/Glibenclamide Tablets to Healthy Human Volunteers

✍ Scribed by GUHAN BALAN; PETER TIMMINS; DOUGLAS S. GREENE; PUNIT H. MARATHE

Book ID
111768522
Publisher
Pharmaceutical Press
Year
2000
Tongue
English
Weight
155 KB
Volume
52
Category
Article
ISSN
2042-7158

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In vitro–in vivo correlation (IVIVC) models for metformin after administration of modified-release (MR) oral dosage forms to healthy human volunteers
✍ Balan, Guhan (author);Timmins, Peter (author);Greene, Douglas S. (author);Marath 📂 Article 📅 2001 🏛 John Wiley and Sons Inc 🌐 English ⚖ 177 KB 👁 1 views

The objective of the current study was to develop and evaluate the internal predictability for level C and A in vitro±in vivo correlation (IVIVC) models for prototype modi®ed-release (MR) dosage forms of metformin. In vitro dissolution data for metformin were collected for 22 h using a USP II (paddl