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In vitro–in vivo correlation (IVIVC) models for metformin after administration of modified-release (MR) oral dosage forms to healthy human volunteers

✍ Scribed by Balan, Guhan (author);Timmins, Peter (author);Greene, Douglas S. (author);Marathe, Punit H. (author)

Publisher
John Wiley and Sons Inc
Year
2001
Tongue
English
Weight
177 KB
Volume
90
Category
Article
ISSN
0022-3549

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In vitro–in vivo correlation (IVIVC) mod
In vitro–in vivo correlation (IVIVC) models for metformin after administration of modified-release (MR) oral dosage forms to healthy human volunteers
✍ Balan, Guhan (author);Timmins, Peter (author);Greene, Douglas S. (author);Marath 📂 Article 📅 2001 🏛 John Wiley and Sons Inc 🌐 English ⚖ 177 KB 👁 1 views

The objective of the current study was to develop and evaluate the internal predictability for level C and A in vitro±in vivo correlation (IVIVC) models for prototype modi®ed-release (MR) dosage forms of metformin. In vitro dissolution data for metformin were collected for 22 h using a USP II (paddl