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In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane

✍ Scribed by Laurent Bédouet; Florentina Pascale; Michel Bonneau; Michel Wassef; Alexandre Laurent

Book ID
116920498
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
1006 KB
Volume
25
Category
Article
ISSN
0887-2333

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✍ Ralf H. Wittenberg; Roland E. Willburger; Karin S. Kleemeyer; Bernhard A. Peskar 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 939 KB

Objective. To determine the major source of eicosanoid release in arthritic joint tissues and to examine the modulation of this release by indomethacin and diclofenac. Methods. Release of prostaglandin E, (PGE,), 6-keto-PGF1,, leukotriene B, (LTB,), and LTC, was measured in supernatants of synovial