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In vitro evaluation and biodistribution of a 99mTc-labeled anti-VEGF peptide targeting neuropilin-1

✍ Scribed by Gérard Y Perret; Anna Starzec; Nathalie Hauet; Jackie Vergote; Marie Le Pecheur; Roger Vassy; Gérard Léger; Kristin A Verbeke; Guy Bormans; Patrick Nicolas; Alfons M Verbruggen; Jean-Luc Moretti


Book ID
116798759
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
131 KB
Volume
31
Category
Article
ISSN
0969-8051

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✍ Lasse N. Waehrens; Jan T. Rasmussen; Christian W. Heegaard; Lise Falborg 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 129 KB

## Abstract Lactadherin is an opsonin, which binds with high affinity to phosphatidylserine exposed on the surface of apoptotic cells via its C1C2 domains. Phagocytosis of the apoptotic cells is then facilitated by an Arg‐Gly‐Asp (RGD)‐ mediated binding to macrophages surface integrins. The present