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In vitro enhancement of erythrocyte mercury uptake by spironolactone

✍ Scribed by Michael C. Kushlan; James E. Haddow; Roger Lester


Book ID
119002188
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
443 KB
Volume
31
Category
Article
ISSN
0041-008X

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The binding of acetazolamide to human erythrocytes was studied in vitro. Blood and plasma samples were analyzed by electron-capture GLC. At 37 degrees, drug equilibrated between plasma and erythrocytes in approximately 40 min. The effect of plasma concentration on the steady-state level of drug with