Effect of inhibitors and substrates on methyl mercury uptake by rat erythrocytes
โ Scribed by Guang Wu
- Book ID
- 105871322
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 667 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0340-5761
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๐ SIMILAR VOLUMES
Previous in v i m studies using the exposure of suspensions of normal human erythrocytes to mercury vapour (Hgo) in Warburg vessels revealed a broad variation of the cellular Hg uptake in the presence of hydrogen peroxide and furnished evidence for an oxidation of Hgo by the catalase-H202 pathway. T
Guanidinoethane sulfonate (GES) markedly decreased 3H-taurine accumulated in the retina by the high-affinity uptake process. The effect of GES was dosedependent. Analysis of the kinetics of GES effect revealed that it is a competitive inhibitor. The uptake of taurine by GES was less affected in rat