In vitro Elution of Gentamicin From Plaster of Paris Beads
β Scribed by Elizabeth M. Santschi; Lisa McGarvey
- Book ID
- 111723751
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 149 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0161-3499
No coin nor oath required. For personal study only.
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The current antibiotics delivery system for orthopedic infection treatment uses polymethylmethacrylate (PMMA) beads as a drug release. However the nonbiodegradable nature of the PMMA necessitates a second operation to remove the beads. This article explores the alternative of using biodegradable pol
## Abstract The use of antibioticβimpregnated polymethylmethacrylate (PMMA) cement beads for the local delivery of antibiotics in the treatment of chronic osteomyelitis has become a standard orthopaedic practice. The increasing resistance to antibiotics of organisms associated with orthopaedic infe