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In vitro effects of bone cement onS. aureus growth and phagocytosis and glucose metabolism of macrophage: A preliminary study

✍ Scribed by Shoji, Hiromu ;Nicastro, Joseph F. ;Rovere, George D. ;Gristina, Anthony G.

Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 376 KB
Volume: 10
Category: Article
ISSN: 0021-9304
DOI: 10.1002/jbm.820100506

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A preliminary study of the effects of Surgical Simplex, mixed for various time periods, was performed on S. aureus growth rate, and phagocytosis and glucose metabolism of macrophage in vitro. Quantitatively, no significant effects of the mixture on S. aureus growth rate were observed. The cement mixed for less than 4 min tended to cause adverse effects on phagocytosis rate and hexose monophosphate shunt activity of macrophage. This information may not be directly applicable to in vivo, but in vitro the cement mixture in a certain situation can cause decreased phagocytosis and hexose monophosphate shunt activity of macrophage.

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