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In-vitro effect of retinoic acid on normal and chronic myeloid leukemia granulopoiesis

✍ Scribed by Massimo Aglietta; Wanda Piacibello; Alessandra Stacchini; Fiorella Sanavio; Felice Gavosto


Book ID
113238506
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
509 KB
Volume
9
Category
Article
ISSN
0145-2126

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## Abstract Although imatinib mesylate (IM) has revolutionized the treatment of chronic myeloid leukemia (CML), some patients develop resistance with progression of leukemia. Alternative or additional targeting of signaling pathways deregulated in bcr‐abl‐driven CML cells may provide a feasible opt