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Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro

✍ Scribed by J. Subhashini; S.V.K. Mahipal; P. Reddanna

Book ID
116333452
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
329 KB
Volume
224
Category
Article
ISSN
0304-3835

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## Abstract Although imatinib mesylate (IM) has revolutionized the treatment of chronic myeloid leukemia (CML), some patients develop resistance with progression of leukemia. Alternative or additional targeting of signaling pathways deregulated in bcr‐abl‐driven CML cells may provide a feasible opt