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In vitro cytotoxicity, in vivo biodistribution and antitumor activity of HPMA copolymer–5-fluorouracil conjugates

✍ Scribed by Fang Yuan; Xuan Qin; Dan Zhou; Qing-Yu Xiang; Min-Ting Wang; Zhi-Rong Zhang; Yuan Huang


Book ID
116438038
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
282 KB
Volume
70
Category
Article
ISSN
0939-6411

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✍ Chou-Chik Ting; John R. Wunderlich; Myrthel E. Hargrove; David Winkler 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 690 KB

## Abstract The present study demonstrates that LICC possess both __in vitro__ and __in vivo__ antitumor activity. The LICC were generated by culturing normal spleen cells with syngeneic peritoneal cells and indomethacin, or with a conditioned medium containing IL 2 with or without a putative new l