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HPMA copolymers with pH-controlled release of doxorubicin: In vitro cytotoxicity and in vivo antitumor activity

✍ Scribed by K Ulbrich; T Etrych; P Chytil; M Jelı́nková; B Řı́hová

Book ID: 114161991
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 805 KB
Volume: 87
Category: Article
ISSN: 0168-3659
DOI: 10.1016/s0168-3659(02)00348-6

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## Abstract The present study demonstrates that LICC possess both __in vitro__ and __in vivo__ antitumor activity. The LICC were generated by culturing normal spleen cells with syngeneic peritoneal cells and indomethacin, or with a conditioned medium containing IL 2 with or without a putative new l