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In vitro characterization of the myelotoxicity of cyclopentenyl cytosine

✍ Scribed by Donna A. Volpe, De-lin Du, Charles K. Grieshaber…

Book ID
120777466
Publisher
Springer
Year
1994
Tongue
English
Weight
30 KB
Volume
35
Category
Article
ISSN
0344-5704

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Measurement of Cyclopentenyl Cytosine 5′
Measurement of Cyclopentenyl Cytosine 5′-Triphosphate in Vitro and in Vivo by Multidimensional High-Performance Liquid Chromatography
✍ R. Agbaria; H. Ford; J.A. Kelley; F.M. Xie; P. Politi; J.L. Grem; D.A. Cooney; V 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 478 KB

Cyclopentenyl cytosine 5'-triphosphate (CPEC-TP) is the active metabolite of the investigational drug cyclopentenyl cytosine (CPEC), a nucleoside analogue which exhibits noteworthy antineoplastic activity against several murine and human tumors in tissue culture, and which is now undergoing Phase I