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In Vitro Characterization of Methotrexate-Loaded Poly(Lactic Acid) Microspheres of Different Molecular Weights

✍ Scribed by Singh, U. V.; Udupa, N.

Book ID
119961603
Publisher
Informa plc
Year
1998
Tongue
English
Weight
433 KB
Volume
5
Category
Article
ISSN
1071-7544

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The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated following intra-articular injection of either MTX solution or controlled release MTX loaded microspheres in healthy rabbit joints. MTX solution or MTX loaded microspheres (size 30-100 mm) (10 mg MTX) was injected in