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In Vitro Assessment of Pancreatic Islet Vitality by Oxymetry

โœ Scribed by K. Zacharovova; Z. Berkova; T. Spacek; J. Kriz; E. Dovolilova; P. Girman; T. Koblas; P. Jezek; F. Saudek


Book ID
116931615
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
102 KB
Volume
37
Category
Article
ISSN
0041-1345

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Islet cell lines were produced by retroviral transduction of SV-40 T antigen to monolayer cultures of neonatal rat islets. One line, RN0-11, showed evolution of phenotypes in vitro. It evolved from a non-hormone secreting cell line to an insulin secreting line. It further developed glucagon producin