In vitro and in vivo photodynamic effects of a new photosensitizer: Tetra(m-hydroxyphenyl)chlorin
โ Scribed by V. Vonarx-Coinsmann; M. T. Foultier; N. Cempel; L. Morlet; A. Combre; T. Patrice
- Book ID
- 110572176
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 852 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0268-8921
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The properties of a new photosensitizer, meso-tetrahydroxyphenyl-chlorin (mTHPC), were studied using W9 cells (Chinese-hamster lung fibroblasts). Comparisons were made with 2 other photosensitizers: photofrin II (PII) and meso-tetrahydroxyphenyl-porphyrin (mTHPP). A main advantage of mTHPC is that i
## Background and objective: To optimize photodynamic therapy, it is necessary to know the distribution of photosensitizer in normal tissue as well as tumors and to know how well animal models match human. this study measured the biodistribution of meta-tetra(hydroxyphenyl) chlorin (mthpc) in three