𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro and in vivo m2 muscarinic subtype selectivity of some dibenzodiazepinones and pyridobenzodiazepinones

✍ Scribed by Victor I Cohen; Biyun Jin; R.Carter McRee; Sheila F Boulay; Emil I Cohen; Virendar K Sood; Barry R Zeeberg; Richard C Reba

Book ID
113994808
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
916 KB
Volume
861
Category
Article
ISSN
0006-8993

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Development of M1 subtype selective musc
Development of M1 subtype selective muscarinic agonists for Alzheimer's disease: Translation of in vitro selectivity into in vivo efficacy
✍ R.D. Schwarz; M.J. Callahan; R.E. Davis; J.C. Jaen; H. Tecle πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 131 KB πŸ‘ 2 views

Clinical trials in Alzheimer's disease (AD) with first generation muscarinic agonists (e.g., arecoline, oxotremorine, pilocarpine) produced inconsistent results due to poor pharmacokinetic properties and a lack of separation between central and peripheral activities observed with these compounds. Se