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In Vitro and in Vivo Evaluation in Rabbits of a Controlled Release 5-fluorouracil Subconjunctival Implant Based on Poly(D,L-lactide-co-glycolide)

โœ Scribed by Guangji Wang; Ian G. Tucker; Michael S. Roberts; Lawrence W. Hirst


Book ID
110344933
Publisher
Springer US
Year
1996
Tongue
English
Weight
965 KB
Volume
13
Category
Article
ISSN
0724-8741

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โœ Wang, Zhaoxu ;Roberge, Christophe ;Dao, L๏ฟฝ H. ;Wan, Ying ;Shi, Guixin ;Rouabhia, ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 820 KB

This study evaluated the in vivo biocompatibility and biodegradation behavior of a novel polypyrrole (PPy)/poly(D,L-lactide) (PDLLA) composite and PPy-coated poly(D,L-lactide-co-glycolide) membranes. Test membranes were implanted subcutaneously in rats for 3-120 days. The biocompatibility was assess