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In-vitro and in-vivo erosion profiles of hydroxypropylmethylcellulose (HPMC) matrix tablets

✍ Scribed by Manish Ghimire; Lee Ann Hodges; Janet Band; Bridget O'Mahony; Fiona J. McInnes; Alexander B. Mullen; Howard N.E. Stevens


Book ID
113693376
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
408 KB
Volume
147
Category
Article
ISSN
0168-3659

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This work describes methodologies based on near infrared chemical imaging (NIR CI) and chemometric data analysis for studying hydration behaviors of prolonged release tablets, which contain a high solubility drug at high load and a hydrophilic polymer hydroxypropylmethylcellulose (HPMC). Hydration s