The peroral (po) bioavailability of nifedipine is reported to range from about 45 to 58% in the rat; this compares favourably to human beings. The metabolism of nifedipine is similar in rats and humans (oxidation of the dihydropyridine ring), with the liver believed to be solely responsible for the
✦ LIBER ✦
In vitro and in vivo assessment of hepatic and extrahepatic metabolism of diazepam in the rat
✍ Scribed by Yasutaka Igari; Yuichi Sugiyama; Yasufumi Sawada; Tatsuji Iga; Manabu Hanano
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 387 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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