During oogenesis the oocyte is arrested in meiosis twice. First at prophase I, then a second time at metaphase I in many invertebrates and in metaphase II in the vast majority of vertebrates. Meiosis resumption is triggered by the sperm. This article examines mechanisms that cause oocytes' arrest in
In the beginning: the initiation of meiosis
β Scribed by Wojciech P. Pawlowski; Moira J. Sheehan; Arnaud Ronceret
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 83 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The mostβcritical point of reproductive development in all sexually reproducing species is the transition from mitotic to meiotic cell cycle. Studies in unicellular fungi have indicated that the decision to enter meiosis must be made before the beginning of the premeiotic S phase. Recent data from the mouse1 suggest that this timing of meiosis initiation is a universal feature shared also by multicellular eukaryotes. In contrast, the signaling cascade that leads to meiosis initiation shows great diversity among species. BioEssays 29:511β514, 2007. Β© 2007 Wiley Periodicals, Inc.
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