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In situ perfusion system for oral mucosal absorption in dogs

✍ Scribed by Hiroshi Yamahara; Takehiko Suzuki; Masakazu Mizobe; Kazuo Noda; Masayoshi Samejima

Book ID
102918467
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
697 KB
Volume
79
Category
Article
ISSN
0022-3549

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Oral mucosal absorption of midazolam in
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A significant amount of orally administered midazolam, an anxiolytic and sedative, may be absorbed by the mucosal membranes in the oral cavity, esophagus, and the stomach. The pH dependence of the opening or closure of a ring in midazolam's molecular structure suggests a pH dependence of the mucosal