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Topical Morphine for Oral Mucositis in Children: Dose Finding and Absorption

✍ Scribed by Bettina N. Nielsen; Gitte Aagaard; Steen W. Henneberg; Kjeld Schmiegelow; Steen H. Hansen; Janne Rømsing

Book ID
113742747
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
114 KB
Volume
44
Category
Article
ISSN
0885-3924

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Oral mucositis and salivary methotrexate
Oral mucositis and salivary methotrexate concentration in intermediate-dose methotrexate therapy for children with acute lymphoblastic leukemia
✍ Ishii, Eiichi ;Yamada, Shin-Ichi ;Higuchi, Shun ;Honjo, Tetsu ;Igarashi, Hisaji 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

The relationship between salivary methotrexate (MTX) concentration and severity of oral mucositis after administration of MTX was investigated in six children with acute lymphoblastic leukemia. They received two administrations of MTX at 500 mgm' with one third given bolusly and the remainder by 24-