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In-situ atomic force microscopy study of β-amyloid fibrillization

✍ Scribed by H.K.L Blackley; G.H.W Sanders; M.C Davies; C.J Roberts; S.J.B Tendler; M.J Wilkinson

Book ID
117979576
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
436 KB
Volume
298
Category
Article
ISSN
0022-2836

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## Abstract Amyloid peptide (Aβ) is the major protein component of plaques found in Alzheimer's disease, and the aggregation of Aβ into oligomeric and fibrillic assemblies has been shown to be an early event of the disease pathway. Visualization of the progressive evolution of nanoscale changes in