𝔖 Bobbio Scriptorium
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In search of partners: linking extracellular proteases to substrates

✍ Scribed by Overall, Christopher M.; Blobel, Carl P.

Book ID
109958717
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
681 KB
Volume
8
Category
Article
ISSN
1471-0072

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It is estimated that proteases comprise nearly 2% of the human genome. Given that the primary structure of all known proteases will soon be available, an important challenge is to define the structure-activity relationships that govern substrate hydrolysis. Ideally this would be accomplished on a ge