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In pursuit of a molecular mechanism for adaptive gene amplification

✍ Scribed by P.J Hastings; Susan M Rosenberg

Book ID
117798812
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
211 KB
Volume
1
Category
Article
ISSN
1568-7864

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## Abstract β‐Catenin nuclear translocation is frequently observed in different types of malignancies, including gastric cancer. In gastric cancer, however, the molecular mechanisms leading to accumulation of this protein in the nucleus remain unknown. In this setting, β‐catenin (__CTNNB1__) mutati