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Improving enzymes for cancer gene therapy

โœ Scribed by Loeb, Lawrence A.; Encell, Lance P.; Landis, Daniel M.

Book ID
109826820
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
104 KB
Volume
17
Category
Article
ISSN
1087-0156

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Prodrug activation enzymes in cancer gen
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โœ Manish Aghi; Fred Hochberg; Xandra O. Breakefield ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB ๐Ÿ‘ 2 views

Among the broad array of genes that have been evaluated for tumor therapy, those encoding prodrug activation enzymes are especially appealing as they directly complement ongoing clinical chemotherapeutic regimes. These enzymes can activate prodrugs that have low inherent toxicity using both bacteria