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Improvement of the Synthesis of Bisdehydrodoisynolic Acid 1

✍ Scribed by Turner, D. L.; Bhattacharyya, Bidyut Kamal; Graber, Robert P.; Johnson, William S.


Book ID
120543622
Publisher
American Chemical Society
Year
1950
Tongue
English
Weight
816 KB
Volume
72
Category
Article
ISSN
0002-7863

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In a project designed to relate the unexpected in vivo and in vitro properties exhibited by (+)-and (-)-bisdehydrodoisynolic acid with their absolute stereochemical structure, an X-ray crystal-structure analysis was undertaken of the highly estrogenic, poorly binding (-) enantiomer. 1 H and 13 C NMR