Improvement of the steps of synthesis of vitamin D3. Production of provitamin D3— 7-dehydrocholesterol
✍ Scribed by R. I. Yakhimovich; N. F. Fursaeva; V. N. Vasilevskaya; A. M. Ter-Stepanyan; N. T. Etaryan
- Book ID
- 112407454
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 376 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0091-150X
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Dimethylphosphate esters of vitamins Dz and D, and of 7-dehydrocholesterol give satisfactory mass spectra under electron impact using the direct introduction probe, while this method is not suitable for the related phosphorodichloridates, which undergo to thermal decomposition-polymerization process
We report on the conversion of cholesterol to A=\*7 -cholestadien-la,3g-diol diacetate (6) the photoprecursor of the physiologically active la-hydroxyvitamin D3,1 via A6-cholesten-la.Sg-diol @a). The latter compound was synthesized by modification of a recently published procedure of Li/liquid NH3 r