Improvement of selectivity and sensitivity by column switching in the determination of glycyrrhizin and glycyrrhetic acid in human plasma by high-performance liquid chromatography
β Scribed by Gerard De Groot; Reinder Koops; Elbert A. Hogendoorn; Cherie E. Goewie; T. Jean; F. Savelkoul; Piet van Vloten
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 751 KB
- Volume
- 456
- Category
- Article
- ISSN
- 1873-3778
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract For the quantification of azasetron in rat plasma samples, a columnβswitching HPLC method was developed and validated. Following dilution of plasma samples with mobile phase A (17βmM potassium phosphate buffer (pH 3.0)) and simple protein precipitation by addition of perchloric acid (60
## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The cleanβup and separation of the samp