Improvement of disseminated lymphangiomatosis with recombinant interferon therapy

✍ Scribed by Caroline Laverdière; Michèle David; Josée Dubois; Pierre Russo; Linda Hershon; Jean-Guy Lapierre

• Book ID: 101273665
• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 165 KB
• Volume: 29
• Category: Article
• ISSN: 8755-6863
• DOI: 10.1002/(sici)1099-0496(200004)29:4<321::aid-ppul13>3.0.co;2-c

✦ Synopsis

Disseminated lymphangiomatosis is a rare disorder with a poor prognosis. We present a case involving a 3-year-old boy who presented with pulmonary infiltrates, multiple lytic lesions of the ribcage, and small cystic lesions in the spleen. Open-lung and bone biopsies revealed disseminated lymphangiomatosis. Significant clinical and radiologic improvement were observed and persisted after 28 months of treatment with recombinant interferon alpha-2b (IFN alpha-2b). No significant toxicity has been observed.