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Improvement in atrophic acne scars by topical adapalene (0.3% gel)

Book ID
122250411
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
49 KB
Volume
70
Category
Article
ISSN
1097-6787

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A multicentre study was conducted to compare clinical safety and efficacy of adapalene 0.1% solution and tretinoin 0.025% gel, both topical treatments for acne, in a once-daily dosage regimen for 12 weeks. A total of 297 patients were enrolled by eight investigators in this randomized, investigator-

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## Background: Topical application of isotretinoin and adapalene has proved effective in treating acne vulgaris. both drugs demonstrate therapeutic advantages and less irritancy over tretinoin, the most widely used treatment for acne. they both act as retinoid agonists, but differ in their affinity