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Improved two-stage tests for stratified phase II cancer clinical trials

✍ Scribed by Myron N. Chang; Jonathan J. Shuster; Wei Hou


Book ID
112207041
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
130 KB
Volume
31
Category
Article
ISSN
0277-6715

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Optimal three-stage designs for phase II
✍ T. Timothy Chen πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 136 KB πŸ‘ 2 views

The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at