๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Improved synthesis of oligonucleoside methylphosphonate analogs

โœ Scribed by Ivan Habus; Theresa Devlin; Radhakrishnan P. Iyer; Sudhir Agrwal


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
405 KB
Volume
6
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Indole: A novel leaving group in the syn
โœ Jian-Chao Wang; George Just ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 269 KB

A P" coupling reagent 3 containing indole group is described. Its usefulness is demonstrated by the synthesis of dinucleoside methylphosphonates and methylthiophosphonates. 8 1997 Elsevier Science Ltd. The oligonucleoside methylphosphonates (MP) show significant potential for antisense therapy.' The

Elimination of transamination side produ
โœ M.P Reddy; Firdous Farooqui; Naeem B Hanna ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 196 KB

The transamination side product formed by the use of dC bz or dC \*~ methylphosphonamidite upon treatment with ethylenediamine has been eliminated by the use of dC Ac methylphosphonamidite. The synthesis and characterization of DMT dC Ac methylphosphonamidite is described.