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Improved Synthesis of Cyclic Tertiary Allylic Alcohols by Asymmetric 1,2-Addition of AlMe 3 to Enones

✍ Scribed by Kolb, Andreas; Zuo, Wei; Siewert, Jürgen; Harms, Klaus; von Zezschwitz, Paultheo


Book ID
121810168
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
338 KB
Volume
19
Category
Article
ISSN
0947-6539

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Alkaloid catalysed asymmetric synthesis.
✍ Henk Pluim; Hans Wynberg 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 211 KB

The cinchona alkaloid catalyzed 1,Caddltlon reaction of selenophenols to cyclohexenols has been shown to proceed with asyannetric lnductlon. Optically active selenium adducts are formed in quantitative chemical and up to 43% enanticmeric yields. The transformation to an optically active chiral ally1