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Improved synthesis and in vitro characterization of chitosan–thioethylamidine conjugate

✍ Scribed by Krum Kafedjiiski; Martin Hoffer; Martin Werle; Andreas Bernkop-Schnürch

Book ID
108069568
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
232 KB
Volume
27
Category
Article
ISSN
0142-9612

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HPMA Copolymer–Doxorubicin–Gadolinium Co
HPMA Copolymer–Doxorubicin–Gadolinium Conjugates: Synthesis, Characterization, and in vitro Evaluation
✍ Bahar Zarabi; Anjan Nan; Jiachen Zhuo; Rao Gullapalli; Hamidreza Ghandehari 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## Abstract This study describes the synthesis, characterization, and __in vitro__ evaluation of __N__‐(2‐hydroxypropyl)methacrylamide (HPMA) copolymer–gadolinium (Gd)–doxorubicin (Dox) conjugates. Copolymers of HPMA were derivatized to incorporate side chains for Gd chelation and Dox conjugation.