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Improved syntheses of acridines. Part V. The dechlorination of 5-chloroacridines and a new synthesis of acridine

✍ Scribed by Albert, Adrien ;Willis, John Bryan

Publisher
Wiley (John Wiley & Sons)
Year
1946
Weight
365 KB
Volume
65
Category
Article
ISSN
0368-4075

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✦ Synopsis

Abstract

B‐Chloroacridine (II) was converted to acridine in 80% yiold by hydrogenation in the presence of potassium hydroxide and ranoy‐nicked catalyst at atmospheric picture followed by oxidation of the resulting acridnn (III) with chromic acid. The scope of the now reaction for the preparation of substituted acridities is discussed, with examples. A critical comparison is made of the various methods available for the preparation of acridine.

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