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Improved solid phase amino acid sequence analysis on non-crosslinked resins

โœ Scribed by J.J. Maher; M.E. Furey; L.J. Greenberg


Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
162 KB
Volume
12
Category
Article
ISSN
0040-4039

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Improved solid phase peptide synthesis o
โœ J.J. Maher; M.E. Furey; L.J. Greenberg ๐Ÿ“‚ Article ๐Ÿ“… 1971 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 130 KB

Most solid phase peptide synthesis today employs the Merrifield type crosslinked resins, although the use of these resins presents problems of steric hindrance, diffusion and slow reaction rates (1). When crosslinked resins are used, only a small fraction of the peptide chains are confined to the su