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Improved procedure for formation of epinephrine and norepinephrine fluorophors by the trihydroxyindole reaction

โœ Scribed by C. Valori; C.A. Brunori; V. Renzini; L. Corea

Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
574 KB
Volume
33
Category
Article
ISSN
0003-2697

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โœฆ Synopsis

In the trihydroxyindole (THI) reaction, epinephrine and norepinephrine are oxidized to adrenochrome and noradrenochrome, which are rearranged in alkali to the strongly fluorescent trihydroxyindole derivatives, adrenolutine and noradrenolutine, respectively. The fluorescence of the lutines is then stabilized by the addition of an antioxidant, Ascorbic acid,

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