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Improved Practical Asymmetric Synthesis of α-Alkylmandelic Acids Utilizing Highly Diastereoselective Alkylation of 5-Aryl-2-(1-naphthyl)-1,3-dioxolan-4-ones

✍ Scribed by Misaki, Tomonori; Ureshino, Satoko; Nagase, Ryohei; Oguni, Yumiko; Tanabe, Yoo


Book ID
120071685
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
113 KB
Volume
10
Category
Article
ISSN
1083-6160

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Synthesis and Diels-Alder reactions of 2
✍ William R. Roush; Amy P. Essenfeld; Joseph S. Warmus; Bradley B. Brown 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 284 KB

Chiral dienophiles l-3 undergo highly exo and diasfereoface selective Die/s-Alder reactions. The Die/s-Alder reactions of 3 are also highly exo selective under Lewis acid catalyzed conditions. In connection with an ongoing effort in the natural products arena we required a highly diastereoselective