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Asymmetric Synthesis of α-Methyl α-Amino Acids by Diastereoselective Alkylation of Optically Active 6-Isopropyl-3-methyl-2,3—dihydro-6H-1,4-oxazin-2-ones

✍ Scribed by Dr. Rafael Chinchilla; Prof. Dr. Larry R. Falvello; Nuria Galindo; Prof. Dr. Carmen Nájera


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
390 KB
Volume
36
Category
Article
ISSN
0044-8249

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Isolation and Synthesis of N-(2-Methyl-3
✍ Ángel Cantín; Pilar Moya; Maria-Angeles Castillo; Jaime Primo; Miguel A. Miranda 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 1 views

Two new natural products, N- (2-methyl-3-oxodec-8-enoyl)corresponding acid chloride, in order to acylate Meldrum's acid. Subsequent aminolysis with pyrrolidine, followed by 2-pyrroline (2) and 2-(hept-5-enyl)-3-methyl-4-oxo-6,7,8,8atetrahydro-4H-pyrrolo[2,1-b]-1,3-oxazine (3), have been methylation