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Improved method for estimating water solubility from octanol/water partition coefficient

✍ Scribed by William M. Meylan; Philip H. Howard; Robert S. Boethling

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
85 KB
Volume
15
Category
Article
ISSN
0730-7268

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πŸ“œ SIMILAR VOLUMES

Correlation of water solubility with oct
Correlation of water solubility with octanol-water partition coefficient: A response
✍ Samuel H. Yalkowsky; Shri C. Valvani πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 233 KB

Water (2.3 M ) dissolved in octanol( 6) reduces solute solubility in octanol, while octanol(4.5 X lO-3M) in water (9) enhances solute solubility in water. To support this point, the solubilities of these three compounds in water-saturated octanol are shown to be reduced by -10-30% because of water s