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Improved liquid chromatographic tandem mass spectrometric determination and pharmacokinetic study of glimepiride in human plasma

✍ Scribed by Constantinos Pistos; Maria Koutsopoulou; Irene Panderi

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
162 KB
Volume
19
Category
Article
ISSN
0269-3879

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A method based on ionspray liquid chromatography/tandem mass spectrometry (LC/MS/MS) was developed for the determination of reserpine in equine plasma. A comparison was made of the isolation of reserpine from plasma by liquid-liquid extraction and by solid-phase extraction. A structural analog, resc