Improved detection of hepatitis B surface antigen (HBsAg) in blood donors by monoclonal radioimmunoassay
✍ Scribed by E. Ben-Porath; J. R. Wands; S. Bar-Shany; C. Huggins; K. Isselbacher
- Book ID
- 114438070
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 425 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0372-1248
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## Abstract HBsAg and anti‐HBs can be detected by double‐antibody radioimmunoassay in a reliable routine overnight assay of sensitivity approaching that of solidphase immunoradiometric assay. The test requires careful standardisation and regular preparation of I^125^‐HBsAg of appropriate quality, b
## Abstract The sensitivity of immunoassays for hepatitis B virus (HBV) surface antigen (HBsAg) detection may be hampered by the presence of mutants involving the major antigenic determinant of the protein. The performance of the VITROS® HBsAg Assay has been shown to be affected by mutations compri