Detection of hepatitis B surface antigen by a monoclonal radioimmunoassay in the serum of alcoholic patients
β Scribed by THIERRY POYNARD; PATRICK MARCELLIN; JACK WANDS; SYLVIE NAVEAU; PASCAL DUBREUIL; JACQUES PILLOT; JEAN-CLAUDE CHAPUT
- Book ID
- 118703752
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 395 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0815-9319
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Serum hepatitis B core antigen (HBcAg) was investigated in 85 patients with chronic hepatitis B virus (HBV) infection using a modified radioimmunoassay technique, based on high molarity treatment of samples to avoid masking of the antigen by the excess homologous antibody. Eighty-eight percent of HB
## Abstract HBsAg and antiβHBs can be detected by doubleβantibody radioimmunoassay in a reliable routine overnight assay of sensitivity approaching that of solidphase immunoradiometric assay. The test requires careful standardisation and regular preparation of I^125^βHBsAg of appropriate quality, b