Improved Chemical Synthesis of UDP-Galactofuranose
β Scribed by Marlow, Allison L.; Kiessling, Laura L.
- Book ID
- 111657580
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 82 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1523-7060
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## Abstract Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. This is a valid objective because galactofuranose is absent in mammals. Two enzymes are involved in the biosynthesis of molecules containing g
idues has become apparent because they play a crucial A method to prepare UDP-galactofuranose (UDProles in the physiology of significant pathogens. Of spe-Galf ) free of UDP-galactopyranose (UDP-Galp) is decial importance, internal r)5-b-D-Galf and r)6-b-Dscribed. The UDP-Galf is synthesized enzymat