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Imprinting in Prader–Willi and Angelman syndromes

✍ Scribed by Robert D Nicholls; Shinji Saitoh; Bernhard Horsthemke

Book ID
114174020
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
267 KB
Volume
14
Category
Article
ISSN
0168-9525

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## Abstract Genomic imprinting is an epigenetic mechanism resulting in the preferential expression of the maternal or paternal alleles of a specific subset of genes in the mammalian genome. A key but relatively unexplored question is how imprints are established in the germline. New observations^(1