Importance of the first design matrix in experimental simplex optimization
✍ Scribed by Tomas Öberg
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 313 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0169-7439
No coin nor oath required. For personal study only.
✦ Synopsis
The basic and modified simplex methods are efficient optimization techniques applied in many fields of chemistry and engineering. Various first design matrices were evaluated on polynomial models with added noise. D-optimal linear design matrices performed better than regular or cornered first simplices in the normal experimental situation. These findings have been implemented in a new experimental design an optimization software, the MultiSimplex w .
📜 SIMILAR VOLUMES
The use of intravascular catheters is frequently associated with coagulase-negative staphylococcal infections. Colonization of catheters depends on the ability of bacteria to attach to artificial surfaces, this process is affected by macromolecules present in the body fluids. We determined the adher
The quinolone antibacterial agent cinoxacin was studied by adsorptive stripping voltammetry making use of its controlled interfacial accumulation on a static mercury drop electrode. Measurements were obtained in differential pulse mode and optimized by experimental design. The chemometric approach a