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Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

✍ Scribed by M.C. Peeters; G.J.P. van Westen; Q. Li; A.P. IJzerman


Book ID
116918993
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
483 KB
Volume
32
Category
Article
ISSN
0165-6147

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The overall structure of the biogenic amine subclass of the G-protein-coupled receptors, and of their ligand binding sites, is discussed with the aim of highlighting the major structural features of these receptors that are responsible for ligand recognition. A comparison is made between biogenic am