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Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E

✍ Scribed by Atsuo Mizuno; Yasuko In; Yuki Fujita; Fumi Abiko; Hiroo Miyagawa; Kunihiro Kitamura; Koji Tomoo; Toshimasa Ishida


Book ID
113620982
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
569 KB
Volume
582
Category
Article
ISSN
0014-5793

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Increased phosphorylation of the translational repressor protein 4E-BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous sarcoma virus (RSV). This was accompanied by its dissociation from the complex with initiation factor eIF4E. The ribosomal S6 protein kinase p70